ILAE-LASSE 2025
07 Mar 2025
09:00-10:00 – Welcome and Introduction to LASSE – Esper Cavalheiro (BR)
10:00-10:30 – Coffee-break
10:30-11:30 – Natural history of the epilepsies: an epidemiological view – Jorge Burneo (CAN)
11:30-12:30 – Key steps for designing an epilepsy research project – Giuseppe Bertini (IT)
12:30-14:00 – Lunch
14:00-15:00 – Translational epilepsy – Basic Neuroscience – José Eduardo Peixoto-Santos (BR)
15:00-16:00 – Translational epilepsy – Clinical Neuroscience – Marco de Curtis (IT)
16:00-16:30 – Coffee-break
16:30-17:30 – Ethics and integrity in scientific research – Giuseppe Bertini (IT)
18:30 – Meeting the tutors
20:00 – Dinner
08 Mar 2025
09:00-10:00 – Understanding functional anatomy of epilepsy through intracerebral stimulation – Laura Tassi (IT)
10:00-11:00 – Seizure-induced brain damage – Marco de Curtis (IT)
11:00-11:30 – Coffee-Break
11:30-12:30 – Preventing epileptogenesis with heating. The value of thermocoagulation in focal epilepsies – Laura Tassi (IT)
12:30-14:00 – Lunch
14:00-15:30 – Basic Issues
GROUP A – EEG – (Neonates and Children) – Loreto Rios (CL) & (Adults and Seniors) – Alicia Bogacz (UY)
GROUP B – Imaging – Fernando Cendes (BR)
GROUP C – Classification and semiology – Nathália Figueiredo (BR) & Elza Márcia Yacubian (BR)
GROUP D – Pharmacotherapy – Peter Wolf (DK) & Katia Lin (BR)
15:30-16:00 – Coffee-break
16:00-17:30 – Basic issues
GROUP B – EEG – (Neonates and Children) – Loreto Rios (CL) & (Adults and Seniors) – Alicia Bogacz (UY)
GROUP C – Imaging – Fernando Cendes (BR)
GROUP D – Classification and semiology – Nathália Figueiredo (BR) & Elza Márcia Yacubian (BR)
GROUP A – Pharmacotherapy – Peter Wolf (DK) & Katia Lin (BR)
17:30 – Contributions of neuroimaging to the understanding of the natural history of epilepsy – Fernando Cendes (BR)
18:30 – Group work
20:00 – Dinner
09 Mar 2025
09:00-10:00 – Prediction tools in genetic epilepsies: the key to early target therapies – Andreas Brunklaus (UK)
10:00-11:00 – How to modify the natural history of genetic DEEs– Kette Valente (BR)
11:00-11:30 – Coffee-break
11:30-12:30 – Modifying genetic epilepsies: results from studies on tuberous sclerosis complex – Sergiusz Józwiak (POL)
12:30-14:00 – Lunch
14:00-15:30 – Basic Issues
GROUP C – EEG – (Neonates and Children) – Loreto Rios (CL) & (Adults and Seniors) – Alicia Bogacz (UY)
GROUP D – Imaging – Fernando Cendes (BR)
GROUP A – Classification and semiology – Nathália Figueiredo (BR) & Elza Márcia Yacubian (BR)
GROUP B – Pharmacotherapy – Peter Wolf (DK) & Katia Lin (BR)
15:30-16:00 – Coffee-break
16:00-17:30 – Basic issues
GROUP D – EEG – (Neonates and Children) – Loreto Rios (CL) & (Adults and Seniors) – Alicia Bogacz (UY)
GROUP A – Imaging – Fernando Cendes (BR)
GROUP B – Classification and semiology – Nathália Figueiredo (BR) & Elza Márcia Yacubian (BR)
GROUP C – Pharmacotherapy – Peter Wolf (DK) & Katia Lin (BR)
17:30 – 18:30 – What to do to improve quality of life in patients with refractory epilepsy – Jaime Carrizosa (CO)
18:30 – Group work
20:00 – Dinner
10 MAR 2025
09:00-10:00 – Alternative and natural remedies in epilepsy care: do they work? – Angelina Kakooza (ANG)
10:00-11:00 – The role of Clinical Neuropsychology in the management of epilepsy – Gus Baker (UK)
11:00-11:30 – Coffee-break
11:30-12:30 – Update on epilepsy and pregnancy – Törbjorn Tomson (SWE)
12:30-14:00 – Lunch
14:00-15:00 – Precipitating factors, prodromes, reflex seizures and the natural history of seizures – Patricia Braga (UY)
15:00-16:00 – SUDEP: incidence, risk factors and potential for prevention – Törbjorn Tomson (SWE)
16:00-16:30 – Coffee-break
16:30-17:30 – Vigabatrin: new data on indications and safety in pediatric epilepsies – Sergiusz Józwiak (POL)
17:30 – 18:30 – The cognitive effects of anti-epileptic drugs – Gus Baker (UK)
18:30 – Group work
20:00 – Dinner
11 Mar 2025
09:00-10:00 – Precision therapy for monogenic epilepsies – Danielle Andrade (CAN)
10:00-11:00 – Antiepileptogenic trials: past, present, and future – Piero Perucca (AUS)
11:00-11:30 – Coffee-break
11:30-12:30 – Sodium channel as an initial door to epileptogenesis – Massimo Mantegazza (FR)
12:30-14:00 – Lunch
14:00-15:00 – Would iPSCs change the natural history of Epilepsies? Bruno Araújo Torres (USA)
15:00 – 16:00 – Pathophysiological mechanisms of epilepsy and migraine – Massimo Mantegazza (FR)
16:00 – 16:30 – Coffee-break
16:30-18:30 – Case-Oriented Study
• Group 2 – Peter Wolf (DK)
• Group 3 – Rüta Mameniskiene (LT)
• Group 1- Katia Lin (BR)
18:30 – Group work
20:00 – Dinner
12 Mar 2025
09:00-10:00 – Precision approaches to prevent and manage epilepsy comorbidities – Piero Perucca (AUS)
10:00-11:00 – Is it possible to eliminate the stigma about epilepsy? One goal and many paths – Alicia Bogacz (UY)
11:00-11:30 – Coffee-break
11:30-12:30 – Social determinants of health and self-management in epilepsies – Barbara Jobst (EUA)
12:30-14:00 – Lunch
14:00-16:00 – Case-Oriented Study
• Group 1 – Peter Wolf (DK)
• Group 2 – Rüta Mameniskiene (LT)
• Group 3 – Katia Lin (BR)
16:00-16:30 – Coffee-break
16:30-18:30 – Case-Oriented Study
• Group 3 – Peter Wolf (DK)
• Group 1 – Rüta Mameniskiene (LT)
• Group 2 – Katia Lin (BR)
18:30-20:00 – Group work
20:00 – Dinner
13 Mar 2025
08:00–09:00 – When and how epilepsy treatment modifies the core symptoms of autism – Guilca Contreras (VE)
09:00–10:00 – What is the role of inflammation in seizure and seizure outcomes in DEE? Stéphane Auvin (FR)
10:00–10:30 – Coffee-break
10:30–11:30 – Can we really modify the trajectory in the tuberous sclerosis complex (TSC)? – Nicola Specchio (IT)
11:30-12:30 – Encephalopathic patterns: Generators and implication in the outcome – Loreto Rios (CL)
12:30-14:00 – Lunch
14:00–15:00 – Deep brain stimulation in epilepsy – Maria Del Carmen Garcia (AR)
15:00-16:00 – The use of EEG as an outcome assessment in clinical trials – Stéphane Auvin (FR)
16:00-16:30 – Coffee-break
16:30-17:30 – Natural history and clinical trial readiness: How far? How close? – Kette Valente (BR)
17:30-18:30 – Autoimmune Seizures and Epilepsies – Ruta Mameniskiene (LT)
18:30 – Group work
20:00 – Dinner
14 Mar 2025
Finalization of the research projects with tutors
Coffee-breaks: 10:30h and 16:00h
Lunch: 12:30h Dinner: 20:00h
15 Mar 2025
Presentation of the research projects
Coffee-breaks: 10:30h and 16:00h
Lunch: 12:30h
Farewell dinner: 20:00h
Tutors:
Bruno Araujo
Giuseppe Bertini
Jaime Carrizosa
Loreto Rios
Luis Eduardo Peixoto-Santos
Maria Del Carmen Garcia
Patricia Braga
Ruta Mameniskiene