Modifying the natural history of the Epilepsies

18th Latin American Summer School on Epilepsy - LASSE XVIII

São Paulo - Brazil

Modifying the natural history of the Epilepsies
18th Latin American Summer School on Epilepsy – LASSE XVIII
São Paulo – Brazil

Applications for LASSE 2025 will be open from 1st October through 30 November 2024

ILAE-LASSE  2025

07 Mar 2025

09:00-10:00 – Welcome and Introduction to LASSE – Esper Cavalheiro (BR)

10:00-10:30 – Coffee-break

10:30-11:30 – Natural history of the epilepsies: an epidemiological view – Jorge Burneo (CAN)

11:30-12:30 – Key steps for designing an epilepsy research project – Giuseppe Bertini (IT)

12:30-14:00 – Lunch

14:00-15:00 – Translational epilepsy – Basic Neuroscience – José Eduardo Peixoto-Santos (BR)

15:00-16:00 – Translational epilepsy – Clinical Neuroscience – Marco de Curtis (IT)

16:00-16:30 – Coffee-break

16:30-17:30 – Ethics and integrity in scientific research – Giuseppe Bertini (IT)

18:30 – Meeting the tutors      

20:00 – Dinner         


08 Mar 2025

09:00-10:00 – Understanding functional anatomy of epilepsy through intracerebral stimulation – Laura Tassi (IT)

10:00-11:00 – Seizure-induced brain damage – Marco de Curtis (IT)

11:00-11:30 – Coffee-Break

11:30-12:30 – Preventing epileptogenesis with heating. The value of thermocoagulation in focal epilepsies – Laura Tassi (IT)

12:30-14:00 – Lunch

14:00-15:30 – Basic Issues

GROUP A – EEG – (Neonates and Children) – Loreto Rios (CL) & (Adults and Seniors) – Alicia Bogacz (UY)

GROUP B – Imaging – Fernando Cendes (BR)

GROUP C – Classification and semiology – Nathália Figueiredo (BR) & Elza Márcia Yacubian (BR)

GROUP D – Pharmacotherapy – Peter Wolf (DK) & Katia Lin (BR)

15:30-16:00 – Coffee-break

16:00-17:30 – Basic issues

GROUP B – EEG – (Neonates and Children) – Loreto Rios (CL) & (Adults and Seniors) – Alicia Bogacz (UY)

GROUP C – Imaging – Fernando Cendes (BR)

GROUP D – Classification and semiology – Nathália Figueiredo (BR) & Elza Márcia Yacubian (BR)

GROUP A – Pharmacotherapy – Peter Wolf (DK) & Katia Lin (BR)

17:30 – Contributions of neuroimaging to the understanding of the natural history of epilepsy – Fernando Cendes (BR)

18:30 – Group work

20:00 – Dinner


09 Mar 2025

09:00-10:00 – Prediction tools in genetic epilepsies: the key to early target therapies – Andreas Brunklaus (UK)

10:00-11:00 – How to modify the natural history of genetic DEEs– Kette Valente (BR)

11:00-11:30 – Coffee-break

11:30-12:30 – Modifying genetic epilepsies: results from studies on tuberous sclerosis complex – Sergiusz Józwiak (POL)

12:30-14:00 – Lunch

14:00-15:30 – Basic Issues

GROUP C – EEG – (Neonates and Children) – Loreto Rios (CL) & (Adults and Seniors) – Alicia Bogacz (UY)

GROUP D – Imaging – Fernando Cendes (BR)

GROUP A – Classification and semiology – Nathália Figueiredo (BR) & Elza Márcia Yacubian (BR)

GROUP B – Pharmacotherapy – Peter Wolf (DK) & Katia Lin (BR)

15:30-16:00 – Coffee-break

16:00-17:30 – Basic issues

GROUP D – EEG – (Neonates and Children) – Loreto Rios (CL) & (Adults and Seniors) – Alicia Bogacz (UY)

GROUP A – Imaging – Fernando Cendes (BR)

GROUP B – Classification and semiology – Nathália Figueiredo (BR) & Elza Márcia Yacubian (BR)

GROUP C – Pharmacotherapy – Peter Wolf (DK) & Katia Lin (BR)

17:30 – 18:30 – What to do to improve quality of life in patients with refractory epilepsy – Jaime Carrizosa (CO)

18:30 – Group work

20:00 – Dinner


10 MAR 2025

09:00-10:00 – Alternative and natural remedies in epilepsy care: do they work? – Angelina Kakooza (ANG)

10:00-11:00 – The role of Clinical Neuropsychology in the management of epilepsy – Gus Baker (UK)

11:00-11:30 – Coffee-break

11:30-12:30 – Update on epilepsy and pregnancy – Törbjorn Tomson (SWE)

12:30-14:00 – Lunch

14:00-15:00 – Precipitating factors, prodromes, reflex seizures and the natural history of seizures – Patricia Braga (UY)

15:00-16:00 – SUDEP: incidence, risk factors and potential for prevention – Törbjorn Tomson (SWE)

16:00-16:30 – Coffee-break

16:30-17:30 – Vigabatrin: new data on indications and safety in pediatric epilepsies – Sergiusz Józwiak (POL) 

17:30 – 18:30 – The cognitive effects of anti-epileptic drugs – Gus Baker (UK)

18:30 – Group work

20:00 – Dinner


11 Mar 2025

09:00-10:00 – Precision therapy for monogenic epilepsies – Danielle Andrade (CAN)

10:00-11:00 – Antiepileptogenic trials: past, present, and future – Piero Perucca (AUS)

11:00-11:30 – Coffee-break

11:30-12:30 – Sodium channel as an initial door to epileptogenesis – Massimo Mantegazza (FR)

12:30-14:00 – Lunch

14:00-15:00 – Would iPSCs change the natural history of Epilepsies? Bruno Araújo Torres (USA)

15:00 – 16:00 – Pathophysiological mechanisms of epilepsy and migraine – Massimo Mantegazza (FR)

16:00 – 16:30 – Coffee-break

16:30-18:30 – Case-Oriented Study

•            Group 2 – Peter Wolf (DK)

•            Group 3 – Rüta Mameniskiene (LT)

•            Group 1- Katia Lin (BR)

18:30 – Group work

20:00 – Dinner


12 Mar 2025

09:00-10:00 – Precision approaches to prevent and manage epilepsy comorbidities – Piero Perucca (AUS)

10:00-11:00 – Is it possible to eliminate the stigma about epilepsy? One goal and many paths – Alicia Bogacz (UY)

11:00-11:30 – Coffee-break

11:30-12:30 – Social determinants of health and self-management in   epilepsies – Barbara Jobst (EUA)

12:30-14:00 – Lunch

14:00-16:00 – Case-Oriented Study

•            Group 1 – Peter Wolf (DK)

•            Group 2 – Rüta Mameniskiene (LT)

•            Group 3 – Katia Lin (BR)

16:00-16:30 – Coffee-break

16:30-18:30 – Case-Oriented Study

•            Group 3 – Peter Wolf (DK)

•            Group 1 – Rüta Mameniskiene (LT)

•            Group 2 – Katia Lin (BR)

18:30-20:00 – Group work

20:00 – Dinner


13 Mar 2025

08:00–09:00 – When and how epilepsy treatment modifies the core symptoms of autism – Guilca Contreras (VE)

09:00–10:00 – What is the role of inflammation in seizure and seizure outcomes in DEE? Stéphane Auvin (FR)

10:00–10:30 – Coffee-break

10:30–11:30 – Can we really modify the trajectory in the tuberous sclerosis complex (TSC)? – Nicola Specchio (IT)

11:30-12:30 – Encephalopathic patterns: Generators and implication in the outcome – Loreto Rios (CL)

12:30-14:00 – Lunch

14:00–15:00 – Deep brain stimulation in epilepsy – Maria Del Carmen Garcia (AR)

15:00-16:00 – The use of EEG as an outcome assessment in clinical trials – Stéphane Auvin (FR)

16:00-16:30 – Coffee-break

16:30-17:30 – Natural history and clinical trial readiness: How far? How close? – Kette Valente (BR)

17:30-18:30 – Autoimmune Seizures and Epilepsies – Ruta Mameniskiene (LT)

18:30 – Group work

20:00 – Dinner


14 Mar 2025

Finalization of the research projects with tutors

Coffee-breaks: 10:30h and 16:00h

Lunch: 12:30h Dinner: 20:00h


15 Mar 2025

Presentation of the research projects

Coffee-breaks: 10:30h and 16:00h

Lunch: 12:30h

Farewell dinner: 20:00h


Tutors:

Bruno Araujo

Giuseppe Bertini

Jaime Carrizosa

Loreto Rios

Luis Eduardo Peixoto-Santos

Maria Del Carmen Garcia

Patricia Braga

Ruta Mameniskiene

Tutors:
Bruno Araujo
Giuseppe Bertini
Jaime Carrizosa
Loreto Rios
Luis Eduardo Peixoto-Santos
Maria Del Carmen Garcia
Patricia Braga
Ruta Mameniskiene